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This will become clear as that chapter unfolds during thedescriptions of real immune-based therapeutic clinical trials for the treatment of cancer.However, now it is time to address these varied and complex Treg-only effector mechanisms.Since this book has the unique design of describing the cellular interactions within aparticular topic and then describing the translational pathways associated with thoseinteractions in a separate section, some of the transduction pathway descriptions here will bebrief.

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